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Introduction

What is cancer

The prostate

What is prostate cancer?

What are the causes?

Screening

What are the symptoms?

How it is diagnosed
Types of treatment used
Surgery
Radiotherapy
Hormone therapy
Chemotherapy
Follow up
Unwanted effects of treatment
Research - clinical trials
Your feelings
If you are a friend or relative
Talking to children
What you can do
Who can help?
Other useful organisations
Helpful books

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Understanding Cancer of the Prostate

From the CancerBACUP booklet series

Obtain free publications

What can be done about unwanted effects of the treatment

Short term unwanted effects of treatments for prostate cancer

TUR

Radical Prostatectomy

Radiotherapy

Hormone Therapy

Urinary incontinence

1

3

1

0

Impotence

0

3

2

3

Diarrhoea / bowel problems

0

1

2

1

Bladder symptoms

3

3

2

0

Hot flushes

0

0

0

3

Tiredness / lack of energy

1

1

1

2

Weight gain

0

0

0

0

       Sore skin

0

0

1

0

Breast Enlargement

0

0

0

1*

Key:
0 = no effect
1 = rare effect (less than 10% of people treated)
2 = possible effect (up to 40% of people treated)
3 = common effect (more that 40% of people treated)

* Breast enlargement is a common effect of flutamide (when used on its own), but rare with other hormone therapies.



Long term unwanted effects of treatments for prostate cancer

TUR

Radical Prostatectomy

Radiotherapy

Hormone Therapy

Urinary incontinence

1

2

1

0

Impotence

1

3

2

3

Diarrhoea / bowel problems

0

1

2

1

Bladder symptoms

0

1

1

0

Hot flushes

0

0

0

3

Tiredness / lack of energy

0

0

0

3

Weight gain

0

0

0

2

Sore skin

0

0

1

0

Breast enlargement

0

0

0

1*

Key:
0 = no effect
1 = rare effect (less than 10% of people treated)
2 = possible effect (up to 40% of people treated)
3 = common effect (more that 40% of people treated)

* Breast enlargement is a common effect of flutamide (when used on its own), but rare with other hormone therapies

Unfortunately, as the tables show, treatment for cancer of the prostate can cause unpleasant and distressing unwanted effects, both short and long-term. Before you have any treatment it is important that you are fully aware of them. Obviously, doctors cannot predict accurately who is going to be affected, which is why it is important that you are fully informed about the risks beforehand and have plenty of opportunity to discuss them. Remember there are often choices to be made about which treatment you should have, or even whether you have any treatment. You can have as large or small a part in those choices as is right for you.

Any course of treatment may make you too tired to be interested in sex. This is known as loss of libido and it is common to many illnesses, not just cancer.

Many men, regardless of age, find it very difficult to talk about such personal subjects as sexual impotence, particularly with their doctor or other medical staff. Impotence may not be permanent and can sometimes be brought on by anxiety rather than the treatment. Men may find it difficult to talk to their partners, for fear of rejection - but these fears are often mistaken. Sexual relationships are built on many things, like love, trust and common experiences. Talk to your partner about your fears and worries.

If you find the loss of your sex life disturbing you should discuss this with your doctor. There are practical ways to help overcome impotence and your doctor will be able to give you further information about these.

Physical devices such as vacuum pumps and constriction rings can help you to achieve and maintain an erection. Implants can be surgically inserted into the penis so that it is permanently semi-erect.

Drug treatments are also available. Alprostadil (Caverject) and papaverine are injections given straight into the penis to achieve erection. These work for many men, although injection can be sore and alprostadil can sometimes cause a painful erection. After careful teaching, men can give themselves these injections.

A newer method is known as MUSE: a small pellet containing alprostadil is put into the tip of the urethra using a special applicator.

Sildenafil (Viagra) is another new form of drug treatment. It is too early to say how many men with impotence as a result of prostate cancer treatment will be helped by this drug, although it has shown some success in men who have impotence after radical prostatectomy. Sildenafil has to be taken about an hour in advance and will only work if you are sexually aroused. It cannot be used by men who take nitrate based medicine for heart problems.

Remember, your doctor is likely to have treated several other men with the same problem so try not to feel embarrassed.

Infertility
Most treatments for cancer of the prostate are likely to cause infertility, which means you will no longer be able to father a child. Following radiotherapy to the prostate infertility is likely. Your doctor or radiotherapist can give you more details of this before you start treatment. This is obviously an important issue to discuss with your partner before you start treatment.

Urinary incontinence
Losing control of your bladder may be caused by the cancer itself or following surgery or radiotherapy. In recent years a lot of progress has been made in dealing with incontinence and there are several different ways of coping with the problem. Don't hesitate to discuss any worries with your doctor or nurse. Some hospitals have medical staff who are specially trained to give advice about incontinence and the Continence Foundation (see chapter: "Useful organisations") can also offer useful information.

It is important to stress that these problems do not affect all men. Ask your doctor as many questions as you like about your treatment and the possible side-effects so you are better prepared to cope if problems do arise.