Q Bar, Regent Street
Glamorous little venue just off Regent Street where, fingers crossed, you wont get too much of the townie rif-raf. Inside there are lavish sofas and 2 dancefloors, one offering mirrors on 3 walls (basically, everywhere you look you see yourself dancing like a muppet), the other is thankfully much darker and mirror-free. It's expensive, as all Regent St clubs are, but it's just about worth it.

12 New Burlington Street, W1
Nearest Tube: Piccadilly / Oxford Circus