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APPROVED DOSAGE: one 300mg yellow-orange tablet twice daily.
CHILDREN: Liquid formulation available.
TIPS ON TAKING: Abacavir can be taken with or without food.
COMMON SIDE-EFFECTS: Nausea and vomiting; headaches; weakness; diarrhoea; insomnia; dizziness, and abdominal pain. An allergic reaction (often involving fever and rash) occurs in 3% of people taking abacavir, usually within four weeks of starting the drug. See your doctor immediately if youdevelop a rash while on abacavir. It is dangerous to re-try abacavir if you have had an allergic reaction to it previously.
RARE SIDE-EFFECTS: Liver problems.
RESISTANCE TO ABACAVIR: Abacavir may be ineffective if you have extensive experience with AZT/3TC and/or ddl.
KEY DRUG INTERACTIONS: No significant drug interactions yet identified.
BRAIN: Abacavir may cross the blood-brain barrier and may be effective against HIV in the brain. Abacavir is also available in a combined form with AZT and 3TC. The AZT/3TC/abacavir pill is called Trizivir. In the UK it is currently only available through an expanded access scheme.
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