NAMES:
Hydroxyurea, Hydrea'
TYPE OF DRUG:
Hydroxyurea inhibits a human enzyme which is used to make human and HIV genetic building blocks. As a consequence of this interference, NRTIs are much more active in cells. When hydroxyurea is used with some NRTIs, particularly ddl, there is an increased anti-HIV
effect.
STATUS:
Licensed to treat leukaemia (cancer of the blood).
DOSAGE:
One pink and grey/blue SOOmg capsule twice a day.
TIPS ON TAKING:
Take with or without food.
COMMON SIDE-EFFECTS:
Blood disorders, nausea, hair loss (all more common at higher doses).
RESISTANCE TO HYDROXYUREA:
Unlikely to occur.
DRUG INTERACTIONS:
Increases anti-HIV effects of some NRTIs and adefovir. Drugs that cause blood disorders may increase the risk of side-effects.
Disclaimer:
The site editor has taken all such care as considered reasonable in preparing the information published, but cannot be held responsible for any inaccuracies or mis-statements of fact contained herein.
